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AIDS Surveillance Case Definition of the U.S. Centers for Disease Control and Prevention  






A diagnosis of AIDS is made whenever a person is HIV-positive and:  

he or she has a CD4+ cell count below 200 cells per microliter OR  
his or her CD4+ cells account for fewer than 14 percent of all lymphocytes OR  
that person has been diagnosed with one or more of the AIDS-defining illnesses listed below.  



AIDS-Defining Illnesses
Candidiasis of bronchi, trachea, or lungs (see Fungal Infections)  
Candidiasis, esophageal (see Fungal Infections)  
Cervical cancer, invasive¢Ô  
Coccidioidomycosis, disseminated (see Fungal Infections)  
Cryptococcosis, extrapulmonary (see Fungal Infections)  
Cryptosporidiosis, chronic intestinal (>1 month duration) (see Enteric Diseases)  
Cytomegalovirus disease (other than liver, spleen, or lymph nodes)  
Cytomegalovirus retinitis (with loss of vision)  
Encephalopathy, HIV-related¢Ó (see Dementia)  
Herpes simplex: chronic ulcer(s) (>1 month duration) or bronchitis, pneumonitis, or esophagitis  
Histoplasmosis, disseminated (see Fungal Infections)  
Isosporiasis, chronic intestinal (>1 month duration) (see Enteric Diseases)  
Kaposi's sarcoma  
Lymphoma, Burkitt's  
Lymphoma, immunoblastic  
Lymphoma, primary, of brain (primary central nervous system lymphoma)  
Mycobacterium avium complex or disease caused by M. Kansasii, disseminated  
Disease caused by Mycobacterium tuberculosis, any site (pulmonary¢Ô or extrapulmonary¢Ó) (see Tuberculosis)  
Disease caused by Mycobacterium, other species or unidentified species, disseminated  
Pneumocystis carinii pneumonia  
Pneumonia, recurrent(see Bacterial Infections)  
Progressive multifocal leukoencephalopathy  
Salmonella septicemia, recurrent (see Bacterial Infections)  
Toxoplasmosis of brain (encephalitis)  
Wasting syndrome caused by HIV infection


Additional Illnesses That Are AIDS-Defining in Children, But Not Adults

Multiple, recurrent bacterial infections¢Ó (see Bacterial Infections)  
Lymphoid interstitial pneumonia/pulmonary lymphoid hyperplasia